“ We demonstrated in TB patients and in a human cell culture model that MT1- MMP expression in TB regulates both collagen destruction and cellular migration. doxycycline for strep throat Bone marrow of C57BL 6 Janvier Laboratories, Saint Berthevin Cedex, France and Central animal facility, Hannover Medical School, Hannover, Germany mice was harvested from femora and tibiae and lineage negative lin cells were purified using MACS separation Lineage Cell depletion kit, Miltenyi, Bergisch Gladbach, Germany. ”